Medications

Lilly Announces Proof of Concept Data for Neutralizing Antibody LY-CoV555 in the COVID-19 Outpatient Setting

INDIANAPOLIS, Sept. 16, 2020 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) today announced proof of concept data from an interim analysis of the BLAZE-1 clinical trial, showing a reduced rate of hospitalization for patients treated with LY-CoV555. The randomized, double-blind, placebo-controlled Phase 2 study evaluated LY-CoV555, a SARS-CoV-2 neutralizing antibody, for the treatment of symptomatic COVID-19 […]

Medications

Sanofi and GSK Initiate Phase 1/2 Clinical Trial of COVID-19 Adjuvanted Recombinant Protein-Based Vaccine Candidate

London, UK and Paris, France 03 September 2020 — Sanofi and GSK announce today the start of the Phase 1/2 clinical trial for their adjuvanted COVID-19 vaccine. The vaccine candidate, developed in partnership by Sanofi and GSK, uses the same recombinant protein-based technology as one of Sanofi’s seasonal influenza vaccines with GSK’s established pandemic adjuvant […]

Medications

Increased use of antibiotics may predispose to Parkinson’s disease

Higher exposure to commonly used oral antibiotics is linked to an increased risk of Parkinson’s disease according to a recently published study by researchers form the Helsinki University Hospital, Finland. The strongest associations were found for broad spectrum antibiotics and those that act against against anaerobic bacteria and fungi. The timing of antibiotic exposure also […]

Medications

Turning to old remedies for new health challenges

The last thing anyone wants during a stay in the hospital is a hospital-acquired infection. Nosocomial infections, as they are called, are on the rise as more pathogens become resistant to drugs currently available. One pathogen tops the list as one of the most common, one of the most frequently fatal, and one of the […]

Medications

FDA urged to investigate use of unapproved anti-opioid implant on prisoners and the homeless

BioCorRx bills itself as a developer of “advanced solutions” for alcohol and opioid addictions. But the California-based company has come under fire for plans to test an unapproved naltrexone implant on Louisiana prison inmates and homeless Philadelphians who are struggling with addiction, in violation of federal laws protecting human research subjects. Only one prisoner actually […]

Medications

New type of drug might ease migraines

(HealthDay)—Migraine sufferers who cannot get relief from existing medications may soon have a novel treatment option, a new trial suggests. The study, of nearly 1,700 patients, found that a pill called ubrogepant worked better than a placebo pill at halting migraines in progress. The drug has not yet been approved by the U.S. Food and […]

Medications

MENACTRIMS guidelines for multiple sclerosis updated

(HealthDay)—In a revised 2019 guideline, published in the January 2020 issue of Multiple Sclerosis and Related Disorders, updated recommendations from the Middle East North Africa Committee for Treatment and Research in Multiple Sclerosis (MENACTRIMS) are presented for the diagnosis and treatment of multiple sclerosis (MS). To prepare the revised guideline, Bassem Yamout, M.D., from the […]

Medications

Beware probiotics in ICU patients

It’s become common for patients in the intensive care unit (ICU), both children and adults, to receive probiotics. Often, they are started at home to counteract diarrhea caused by antibiotics. There is also interest in using probiotics proactively in the ICU. A large multicenter clinical trial in Canada is testing whether probiotics would prevent ventilator-associated […]