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The study, published in the journal Nature and part-funded by the UK charity Worldwide Cancer Research, uncovers how palmitic acid alters the cancer genome, increasing the likelihood the cancer will spread. The researchers have started developing therapies that interrupt this process and say a clinical trial could start in the next couple of years. Metastasis—or […]
Scientists at Mount Sinai have created a library of well-characterized human induced pluripotent stem cell (hiPSC) lines from clinically healthy humans, which can serve as a valuable resource of normal controls for in vitro human development, genotype-phenotype association studies, many disease models, and drug response evaluations. This gender-balanced, racially- and ethnically-diverse library of hiPSC lines […]
A new study published today in Nature Neuroscience has uncovered neuronal circuitry in the brain of rodents that may play an important role in mediating pain-induced anhedonia—a decrease in motivation to perform reward-driven behaviors. In the study funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, researchers were […]
The Catholic University of Valencia and Valencian company Visor Medical, manufacturer of preventive health technology for innovation, have released a type IIR surgical mask with an intelligent fabric that can instantaneously deactivate the SARS-COV-2 virus that is responsible for COVID19. The intelligent fabric of these masks has been created thanks to the work of a […]
In the progressing field of immunotherapy, surprisingly little is known about immunity to metastatic tumors in locations such as lymph nodes, a frequent place where cancers first spread. Not only do lymph nodes act as a gateway for cancer cells to travel throughout the body, but they are also home to infection-fighting white blood cells […]
The research team led by Prof. Wei Haiming and Prof. Tian Zhigang from Division of Life Sciences and Medicine, University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS), collaborating with the research group led by Prof. SUN Zimin from the First Affiliated Hospital of USTC revealed the pathological mechanism […]
KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common drivers of cancer and its mutations can be detected in around 25 percent of human tumors. The development of KRAS inhibitors is, thus, an extremely active line of research. Effective results have been elusive so […]
Clinicians and surgeons are increasingly using medical devices based on artificial intelligence. These AI devices, which rely on data-driven algorithms to inform health care decisions, presently aid in diagnosing cancers, heart conditions and diseases of the eye, with many more applications on the way. Given this surge in AI, two Stanford University faculty members are […]
Half of the Danish population are overweight, while 17 percent live with obesity. Worldwide, almost 40 procent have overweight and 13 procent live with obesity. The condition is associated with increased risk for early death, as well as sequelae such as type 2 diabetes, cardiovascular diseases, cancer, and infertility. Weight regain after an initial successful […]
Spinal cord nerve cells branching through the body resemble trees with limbs fanning out in every direction. But this image can also be used to tell the story of how these neurons, their jobs becoming more specialized over time, arose through developmental and evolutionary history. Salk researchers have, for the first time, traced the development […]