Health Problems

Research provides insight into genetic link to potential treatment response among BRCA1/2 breast cancer patients

New findings from researchers in the Perelman School of Medicine at the University of Pennsylvania provide clues about immune response of tumors in patients with BRCA 1/2-related breast cancers. The research, published in the journal Clinical Cancer Research, could shape treatment strategies and clinical trial design for these patients, who make up about two percent […]

Health Problems

Study provides new insights into the role of aging in heart failure

A team led by Massachusetts General Hospital (MGH) investigators has found that activity of an important signaling pathway increases with aging and with heart failure. In their report published in Science Translational Medicine, they describe evidence from both humans and animal models that increased activin type II receptor (ActRII) activity correlates with worsening heart failure […]

Personal Health

Single CRISPR treatment provides long-term benefits in mice

Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease—Duchenne muscular dystrophy (DMD)—for more than a year in mice, despite observed immune responses and alternative gene editing outcomes. The study appears online on February 18 in the journal Nature Medicine. In […]