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Exposure to C. difficile in infancy produces an immune response that might protect against this gastrointestinal infection later in childhood, according to a study published in Clinical Infectious Diseases journal. Researchers found that infants who were naturally exposed to C. difficile in the environment and became colonized with the bacteria had antibodies in their blood. […]
HIV-infected cells release vesicles that contain a viral protein called Nef, impairing cholesterol metabolism and triggering inflammation in uninfected bystander cells, according to a study published July 25 in the open-access journal PLOS Pathogens by Dmitri Sviridov of the Baker Heart and Diabetes Institute in Australia, and colleagues. The findings may explain how HIV infection […]
Cells in the body are wired like computer chips to direct signals that instruct how they function, research suggests. Unlike a fixed circuit board, however, cells can rapidly rewire their communication networks to change their behaviour. The discovery of this cell-wide web turns our understanding of how instructions spread around a cell on its head. […]
TBI is the leading cause of death and disability in people under 45 in developed countries. The primary injury, caused by the initial force from a fall or car accident for example, is followed by a secondary injury which develops in the minutes, hours and days afterwards. This secondary injury is largely responsible for the […]
Scientists at the University of Bonn have developed a method with which an enzyme at work can be “photographed.” Their method makes it possible to better understand the function of important biomolecules. The researchers also hope to gain insights into the causes of certain enzyme disorders. The study will be published in the journal Chemistry […]
Communicable diseases including dengue continue to be major causes of morbidity and mortality in the Philippines. Now, researchers reporting in PLOS Neglected Tropical Diseases have reviewed 60 years of published literature on dengue in the country to identify trends in previous studies and areas where more research is needed. The Philippines is an archipelago of […]
Zebrafish, in contrast to humans, have outstanding regenerative capacities: If brain cells are lost due to illness or injury, they will easily regrow from so-called progenitor cells. With sophisticated methods, researchers from the German Center for Neurodegenerative Diseases (DZNE) and the Technische Universität Dresden (TUD) have now characterized these progenitor cells in great detail and […]
Michigan State University scientists have linked a common food preservative to an altered immune response that possibly hinders flu vaccines. The study conducted in mice, presented at the 2019 Experimental Biology meeting in Orlando, Fla., April 7 at 9 a.m., offers up a new potential factor in vaccine effectiveness. Tert-butylhydroquinone, or tBHQ, can be found […]
The results of a study led by a team from the Barcelona Institute for Global Health (ISGlobal), a centre supported by “la Caixa,” suggest that the risk of a child developing symptoms of attention deficit hyperactivity disorder (ADHD) may be modulated by the mother’s diet during pregnancy. The study, published in the Journal of Pediatrics, […]
Bioscientists are moving closer to 3D-printed artificial tissues to help heal bone and cartilage typically damaged in sports-related injuries to knees, ankles and elbows. Scientists at Rice University and the University of Maryland reported their first success at engineering scaffolds that replicate the physical characteristics of osteochondral tissue — basically, hard bone beneath a compressible […]