More than a year into the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the difference in the severity of the clinical syndrome by country-wide income levels has become clear. A new preprint, released on the medRxiv* server, examines some patterns revealed by a study of the factors […]
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Researchers learn that pregnant women pass along protective COVID antibodies to their babies
Researchers Learn that Pregnant Women Pass Along Protective COVID Antibodies to their Babies Antibodies that guard against COVID-19 can transfer from mothers to babies while in the womb, according to a new study from Weill Cornell Medicine and NewYork-Presbyterian researchers published in the American Journal of Obstetrics and Gynecology. This discovery, published Jan. 22, adds […]
Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments
By capitalizing on a convergence of chemical, biological and artificial intelligence advances, University of Pittsburgh School of Medicine scientists have developed an unusually fast and efficient method for discovering tiny antibody fragments with big potential for development into therapeutics against deadly diseases. The technique, published today in the journal Cell Systems, is the same process […]
Nanobodies protect against SARS-CoV-2 variants in animal model
As of today, the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than 108 million individuals and claimed the lives of nearly 2.7 million globally. This past year management of the COVID-19 pandemic solely relied on non-pharmaceutical interventions such as school closures, physical distancing, shielding of those at heightened risk, and […]
Breastfeeding mothers produce COVID-19 antibodies capable of neutralizing virus
Breastfeeding women with COVID-19 do not pass along the SARS-CoV-2 virus in their milk but do transfer milk-borne antibodies that are able to neutralize the virus, a multi-institutional team of researchers led by the University of Idaho reported. The team analyzed 37 milk samples submitted by 18 women diagnosed with COVID-19. None of the milk […]
Bioengineered ankyrin compounds show high in vitro activity against SARS-CoV-2 mutants
The ongoing coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resisted successful containment by most non-pharmaceutical measures. Vaccination and natural immunity appear to be the only definitive methods to attain population immunity, and thus lead to a return to global normalcy. However, effective therapies continue to be sought […]
SARS-CoV-2 escape mutations identified against monoclonal antibodies and polyclonal immune sera
With the coronavirus disease 2019 (COVID-19) pandemic showing no signs of ending soon, the definitive way out is the achievement of population immunity by either vaccination or natural infection. With the unacceptably high mortality rates associated with the latter route, the development of effective vaccines that can induce neutralizing antibodies against the disease’s causative agent […]
India's Covaxin vaccine likely effective against UK SARS-CoV-2 variant: Study
The worldwide increase in the circulation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the crossing of the shocking milestone of 100 million reported cases. Among the chief causes of growth in infection numbers have been the emergence of new variants, notably the UK variant, with increased infectivity relative to the […]
Allergen Detection Using LC-MS
Allergens are defined as any substances that can cause an allergic reaction. Allergens can be extremely dangerous, so being able to detect them in various substances is very important. Liquid chromatography-mass spectrometry is one method that has gained a lot of popularity over the past decade for the detection of allergens. Kateryna Kon | Shutterstock […]
Benlysta
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. BENLYSTA for injection belimumab (rmc) 120 mg and 400 mg powder; belimumab (rmc) 200 mg in 1 mL solution Consumer Medicine Information What is in this leaflet Please read this leaflet carefully before you are given BENLYSTA. This leaflet answers some common […]