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After collecting data and comparing it with every known mammal and bird species on Earth, scientists from the University of California, Davis, have identified wildlife species that are the most likely to host flaviviruses such as Zika, West Nile, dengue and yellow fever. Flaviviruses are known to cause major epidemics and widespread illness and death […]
For many people, the winter months bring a form of depression called seasonal affective disorder (SAD). SAD is characterized by symptoms such as daily feelings of sadness or depression, lack of energy, problems with sleeping, moodiness, changes in appetite and loss of interest in usual activities. “It is most common among people who live far […]
Monoamine oxidase (MAO) inhibitors are potential drug candidates for treating neurological disorders such as anxiety, Alzheimer’s disease and Parkinson’s disease. This review presents information about MAO inhibitory effects of the umbelliferone based derivatives. The potential antioxidant effects of the derivatives were evaluated by DPPH and H2O2 scavenging methods. The derivatives were screened for hMAO-A and […]
(HealthDay)—For patients with a recent acute coronary syndrome receiving a statin, the price of alirocumab would have to be reduced to be cost-effective, according to a study published online Jan. 1 in the Annals of Internal Medicine. Dhruv S. Kazi, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues examined the cost-effectiveness […]
Researchers will study the gut health of people with Alzheimer’s to see if diet can play a role in managing the behavioural and psychological symptoms of the disease. The University of Aberdeen study, which is the first of its kind, will recruit participants from local care homes. The population of microbes, including bacteria, inside the […]
Taking antidepressants for depression, having post-traumatic stress disorder or anxiety diagnosed by a doctor are risk factors for a disruptive and sometimes violent sleep disorder called rapid eye movement (REM) sleep behavior disorder, according to a study published in the December 26, 2018, online issue of Neurology, the medical journal of the American Academy of […]
A meta-analysis of randomized controlled trials found that catheter ablation was superior to conventional drug therapy alone for patients with atrial fibrillation and heart failure. Findings are published in Annals of Internal Medicine. Atrial fibrillation is associated with thromboembolic stroke, systemic embolism, and decompensated heart failure. Catheter ablation is an established therapeutic strategy for atrial […]
(HealthDay)—Patients should avoid a class of antibiotics called fluoroquinolone due to an increased risk of heart vessel tears associated with their use, the U.S. Food and Drug Administration warned. “These tears, called aortic dissections, or ruptures of an aortic aneurysm can lead to dangerous bleeding or even death,” the agency said in a statement issued […]
During the end-of-year holidays families often come together to exchange gifts and, sometimes, to confront long-held grudges. What better gift than a peace offering? Conflict is rarely pleasant and arguments in families can be particularly upsetting. We all know that knot in the pit of the stomach, the flushed face and sweaty hands we experience […]
In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina (MUSC) report that they have identified a potential therapeutic target for lung fibrosis or scarring. They showed in a preclinical model that the protein promotes fibrosis by turning on profibrotic genes and increasing levels of profibrotic factors, including […]