Health Problems

Catheter ablation superior to standard drug therapy for heart failure

A meta-analysis of randomized controlled trials found that catheter ablation was superior to conventional drug therapy alone for patients with atrial fibrillation and heart failure. Findings are published in Annals of Internal Medicine. Atrial fibrillation is associated with thromboembolic stroke, systemic embolism, and decompensated heart failure. Catheter ablation is an established therapeutic strategy for atrial […]

Health Problems

Certain antibiotics tied to deadly heart vessel tears: FDA

(HealthDay)—Patients should avoid a class of antibiotics called fluoroquinolone due to an increased risk of heart vessel tears associated with their use, the U.S. Food and Drug Administration warned. “These tears, called aortic dissections, or ruptures of an aortic aneurysm can lead to dangerous bleeding or even death,” the agency said in a statement issued […]

Health Problems

Potential therapeutic target for lung fibrosis identified

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina (MUSC) report that they have identified a potential therapeutic target for lung fibrosis or scarring. They showed in a preclinical model that the protein promotes fibrosis by turning on profibrotic genes and increasing levels of profibrotic factors, including […]

Health Problems

New memory study first to use intracranial recordings

Declarative memory—memories that can be consciously recalled—is critical to everyday life. Throughout childhood and adolescence, declarative memory improves remarkably. However, until most recently, there was a critical gap in our understanding of how maturation of the prefrontal cortex drives memory development. A team of researchers led by Noa Ofen, Ph.D., associate professor of psychology in […]

Health Problems

What prevents remyelination? New stem cell research reveals a critical culprit

New research on remyelination, the spontaneous regeneration of the brain’s fatty insulator that keeps neurons communicating, could lead to a novel approach to developing treatments for multiple sclerosis (MS) and other inflammatory diseases. The pre-clinical findings published today in Cell Reports by a University at Buffalo team reveal that activation of a specific transcription factor […]