Health Problems

Hepatocellular carcinoma diagnosis, prognosis and treatment may improve by identifying a protein

Analysing the levels of a protein called TonEBP could provide valuable insight into the likelihood of recurrence of hepatocellular carcinoma, an aggressive cancer of the liver, following its surgical removal. Drugs that target TonEBP could also be investigated for liver cancer treatment. Tonicity-responsive enhancer-binding protein (TonEBP) helps protect cells from stress, but also elevates the […]

Personal Health

Single CRISPR treatment provides long-term benefits in mice

Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease—Duchenne muscular dystrophy (DMD)—for more than a year in mice, despite observed immune responses and alternative gene editing outcomes. The study appears online on February 18 in the journal Nature Medicine. In […]

Health News

BCG treatment for bladder cancer: What to know

In this article, we will discuss what Bacillus Calmette–Guerin (BCG) therapy is, when doctors use it, and what to expect during treatment. We also cover side effects, alternative treatment options, and the outlook associated with bladder cancer. What is BCG therapy? BCG is a bacterium similar to that which gives rise to tuberculosis (TB). However, […]

Health Problems

Discovery could improve cystic fibrosis treatment

Researchers exploring the effects of a long-standing treatment for cystic fibrosis have discovered a potential new target for drugs to treat the disease, which has no cure and typically cuts decades off the lives of patients. The research, a collaboration between the University of Saskatchewan in Canada and UC Berkeley, is based on a unique […]

Health Problems

New treatment approach for leukemia

The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia. The gene causes white blood cells to become leukemia cells that reproduce out of control. Earlier studies by the research group of Veronika Sexl at Vetmeduni Vienna had already […]

Medications

Reata Announces Clinical Trial Design for FALCON, a Phase 3 Trial of Bardoxolone Methyl for the Treatment of Autosomal Dominant Polycystic Kidney Disease

IRVING, Texas, Jan. 03, 2019 (GLOBE NEWSWIRE) — Reata Pharmaceuticals, Inc. (Nasdaq: RETA), a clinical-stage biopharmaceutical company, today announced that it has completed a successful end-of-Phase 2 meeting with the United States Food and Drug Administration (FDA) regarding the design of a Phase 3 clinical trial of bardoxolone methyl (bardoxolone) in patients with autosomal dominant […]