Health Problems

Poor kidney function linked to higher cancer risk

A new study has uncovered a modestly higher cancer risk in individuals with mild to severe chronic kidney disease, driven primarily by skin (non-melanoma) and urogenital cancers. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), do not prove a causal link between kidney dysfunction […]

Health Problems

New kidney research sheds light on harms of certain drugs

Scientists have identified an enzyme that is a “master regulator” of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals. As reported in Nature Communications, a global research team led by the University of Bristol studied how the […]

Medications

Reata Announces Clinical Trial Design for FALCON, a Phase 3 Trial of Bardoxolone Methyl for the Treatment of Autosomal Dominant Polycystic Kidney Disease

IRVING, Texas, Jan. 03, 2019 (GLOBE NEWSWIRE) — Reata Pharmaceuticals, Inc. (Nasdaq: RETA), a clinical-stage biopharmaceutical company, today announced that it has completed a successful end-of-Phase 2 meeting with the United States Food and Drug Administration (FDA) regarding the design of a Phase 3 clinical trial of bardoxolone methyl (bardoxolone) in patients with autosomal dominant […]