Medications

Drug companies near global settlement over opioid crisis

Three leading American drug distributors and an Israeli drugmaker blamed for a deadly US opioid epidemic settled a bellwether civil lawsuit with two Ohio counties Monday, opening the door for a broader national settlement worth billions of dollars. The $260 million deal with Ohio’s Summit and Cuyahoga counties set the basis for a resolution of […]

Medications

Engineering antibodies for diagnosis and immunotherapy

Professor John Whitelock is improving the smarts of antibodies and sending them into the extracellular area to outwit those clever cancer cells. The use of antibodies in cancer therapeutics has gone in and out of favor in the 25-odd years since scientists started investigating them. But according to Professor John Whitelock, from the UNSW Graduate […]

Medications

Some states, towns skeptical over proposed opioid settlement

An offer from OxyContin maker Purdue Pharma and the Sackler family to settle some 2,000 lawsuits over their contribution to the national opioid crisis is receiving growing pushback from state and local officials who say the proposed deal doesn’t include enough money or accountability. Connecticut Attorney General William Tong on Friday called for the company, […]

Medications

Netarsudil lowers IOP in glaucoma, ocular hypertension

(HealthDay)—Netarsudil ophthalmic solution (0.02 percent; once daily) significantly reduced mean intraocular pressure (IOP) among patients with open-angle glaucoma or ocular hypertension, according to a study published in the August issue of the American Journal of Ophthalmology. In a double-masked, randomized, phase 3, noninferiority study, Albert S. Khouri, M.D., from the Rutgers New Jersey School of […]

Medications

Brand-name drug prices rising at slower pace, lower amounts

Drug companies are still raising prices for brand-name prescription medicines, just not as often or by as much as they used to, according to an Associated Press analysis. After years of frequent list price hikes, many drugmakers are showing some restraint, according to the analysis of drug prices provided by health information firm Elsevier. In […]

Medications

OxyContin maker Purdue agrees to provide research data

The maker of the powerful painkiller OxyContin has agreed to provide access to propriety research and other data to researchers at Oklahoma State University to help them find causes and treatments for drug addiction. Stamford, Connecticut-based Purdue Pharma announced the agreement Thursday in a joint statement with the university. Purdue said it will provide Oklahoma […]

Medications

Cancer biologists identify new drug combo

When it comes to killing cancer cells, two drugs are often better than one. Some drug combinations offer a one-two punch that kills cells more effectively, requires lower doses of each drug, and can help to prevent drug resistance. MIT biologists have now found that by combining two existing classes of drugs, both of which […]