Medications

FDA Approves Balversa

April 12, 2019 — The U.S. Food and Drug Administration today granted accelerated approval to Balversa (erdafitinib), a treatment for adult patients with locally advanced or metastatic bladder cancer that has a type of susceptible genetic alteration known as FGFR3 or FGFR2, and that has progressed during or following prior platinum-containing chemotherapy. Patients should be […]

Medications

Drug interaction causes hypotension

The commonly used muscle relaxant tizanidine can lower blood pressure. Tizanidine is metabolized by the enzyme CYP1A2, and concurrent use of tizanidine and a CYP1A2 inhibitor, such as ciprofloxacin, greatly increases tizanidine plasma concentrations. Despite package insert warnings, tizanidine and CYP1A2 inhibitors are commonly co-prescribed. Cecilia Chung, MD, and colleagues used electronic health records to […]

Medications

Pain clinics could cut down on opioid use, team finds

Chronic non-cancer pain is sometimes managed with high-dose opioids, which has partially contributed to the current opioid epidemic. New research from pain specialists at the University of Arizona and Banner – University Medicine may provide options other than opioids for patients with non-cancer chronic pain. “Our study shows the possible potential of pain clinics in […]

Medications

New lockbox helping curb opioid addiction

Addiction treatment centers have long had trouble retaining patients in medication assisted treatment. However, medication-assisted treatment is an approach used for addiction recovery that utilizes medications like Suboxone, Vivitral, and Methadone to reduce opioid cravings, withdrawals and illicit drug use. It has been shown to cut the risk of opioid overdose in half. Even if […]

Medications

How new ketamine drug helps with depression

On March 5, the Food and Drug Administration (FDA) approved the first truly new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine—an anesthetic that has made waves for its surprising antidepressant effect. Because treatment with esketamine might be so helpful to patients with treatment-resistant depression (meaning […]

Medications

FDA Approves Sunosi

DUBLIN, March 20, 2019 /PRNewswire/ — Jazz Pharmaceuticals plc today announced that the U.S. Food and Drug Administration (FDA) approved Sunosi (solriamfetol) to improve wakefulness in adult patients with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea (OSA). Once-daily Sunosi is approved with doses of 75 mg and 150 mg for patients with […]

Medications

‘Inactive’ ingredients may not be, study finds

Most pills and capsules, whether over-the-counter or prescription, include components other than the actual drug. These compounds, known as “inactive ingredients,” help to stabilize the drug or aid in its absorption, and they can make up more than half of a pill’s mass. While these components are usually considered benign, a new study from MIT […]